Especially useful shortcuts for Internet Explorer, from the May 6, 2003 issue of PC magazine:

Ctrl-W: Close the current window (this is especially helpful for foiling pop-ups).

Ctrl-D: Bookmark the current page.

Ctrl-N: Open a new browser window.

F5: Refresh the page.

Ctrl-F5: Fully refresh the page, regardless of caching.

Alt-<Left/Right Arrow>: Go back/forward a page.

Alt-Home: Jump to the home page.

Ctrl-<mouse wheel>: Increase/decrease the default font size.

Shift-<mouse wheel>: Go forward/back a page.

Shift-<left mouse click>: Open a link in a new browser window.

Right mouse button: Open a context-sensitive menu for a link or picture.